MicroRNA Profiling in Benign and Malignant Conjunctival Melanocytic Lesions
نویسندگان
چکیده
منابع مشابه
Myeloid leukemia-1 expression in benign and malignant melanocytic lesions.
Myeloid leukemia-1 (Mcl-1) is an anti-apoptotic protein implicated in tumor progression. Its expression was found to be elevated in many types of human cancers and is correlated with tumor progression. The expression of Mcl-1 in melanoma is not fully understood. We investigated the expression of Mcl-1 in normal nevi, dysplastic nevi, primary melanoma and melanoma metastases by tissue microarray...
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BACKGROUND/AIMS The authors investigated the expression of S100A1, S100A6, S100B, MelanA, and CEA in conjunctival naevi, primary acquired melanosis (PAM), conjunctival melanoma, and uveal melanoma in order to assess their potential usefulness in the pathological differential diagnosis of these entities. METHODS Paraffin embedded sections of 18 conjunctival naevi, 14 PAM, 16 conjunctival melan...
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PURPOSE To gain a better understanding of the molecular events leading to the development of conjunctival melanocytic lesions and conjunctival melanoma, this study was conducted to investigate the presence of T1799A BRAF oncogenic mutation in these lesions. METHODS Forty-eight surgically excised conjunctival melanocytic lesions from 48 patients were examined for the presence of the BRAF T1799...
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ژورنال
عنوان ژورنال: Ophthalmology
سال: 2020
ISSN: 0161-6420
DOI: 10.1016/j.ophtha.2019.10.008